With Lukaku up against a strong side in Arsenal and Sanchez coming up against a solid Everton side, Kane can prey on relegated Hull City.
The England worldwide is in line to collect his second Golden Boot in a row and is only the fifth player since the Premier League began to score 25 or more goals in successive seasons, following in the footsteps of Robbie Fowler, Thierry Henry, Alan Shearer and Robin van Persie.
Tottenham's Harry Kane was all smiles following his four-goal performance against Leicester City.
Son Heung-min scored Spurs' other two in the rout, with Ben Chilwell netting what proved to be scant consolation for last season's champions.
Son found the bottom corner from a Dele Alli flick over Leicester's defence to double Tottenham's tally in the 36th minute.
"I'm not resting on my laurels, and I'll go to Hull looking to get four more hopefully".
"I felt good, Leicester made it tough for us, they put the pressure on to get the goal back, but to get that third goal was vital and the game opened up".
"We had been talking about (the season not being over) during the weekend".
English soccer introduces retrospective bans for simulation
If the proposals are voted through, a fast-track three-man panel of experts will study video evidence of contentious incidents. The Football Association (FA) will have the power to retrospectively punish players for simulation from next season.
Alli will surly be one of the players whom Pochettino will want to keep at all costs, because allowing him to leave, irrelevant of how much they are offered for his services, would send out the message that the club lack ambition.
"To be fair to him and the team, it's a very good collective effort throughout the whole season but we feel so proud of Harry".
Safe to say, it will certainly be interesting who comes out on top for the battle of the best striker but Kane is no doubt the heavy favourite.
Tottenham Hotspur have enjoyed a successful Premier League campaign thus far.
Tottenham moved to 83 points on the season, two more than Leicester's title-winning total a year ago.
"I don't know, you'll have to ask the owners about that", he said.
Not only that, Kane is slowly moving up the table of past goalscorers in the top flight. "We need to put it right for Sunday because we want to finish as high as we can".