Rami Abdel Rahman, the head of the Syrian Observatory for Human Rights (SOHR), a UK-based monitoring group, said on Thursday that a man was killed early in the day in air strikes on Tal Dahab village near Al-Houla town in central Syria. He made more than 330 000 dead and millions of displaced persons and refugees.
"De-escalation zones" were announced in May by opposition backer Turkey and regime allies Iran and Russian Federation after talks in Kazakhstan.
Air strikes have also pummelled rebel-held parts of the Jobar district of Damascus and the adjacent district of Ain Tarma.
According to the OSDH, the suicide bomber blew up an explosive belt in a database used by Jaish al-Islam (army of islam) near the station border Nasib.
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The attack was not claimed in the immediate future, but jihadists linked to the group islamic State (IS) have already attacked the rebels in the south of Syria. Such violations would be curious, as while Syria is taking territory further south, along the Jordan border, there doesn't appear to be any real military reason for the strikes in either zone.
Another rebel spokesman said the army gains were helped by a sudden pull-back by Jaish al-Ashair rebel group, which is backed by Jordan and had been responsible for patrolling that stretch of the border.
The fourth zone, in northwestern Idlib province, has yet not become active.
Syria's uprising erupted in Daraa province in March 2011 with widespread protests calling for the ouster of President Bashar al-Assad.