But Arsene Wenger's double change turned the game, FA Cup final hero Ramsey drilling in an 83rd-minute equalizer and Giroud notching the victor two minutes later with a header that hit the bar and bounced over the line. However, after settling back into Premier League life and getting a win under their belt, Arsenal will be looking for a more comfortable win this time round. Three minutes later, Leicester City equalized.
From Hector Bellerin's lay-off, Mohamed Elneny swept a first-time cross into the box and Lacazette deftly glanced a header past Kasper Schmeichel before spreading his arms to take the acclaim of the crowd.
Cech, who holds the Premier League record for clean sheets, admitted that conceding three goals at home was not "an ideal start".
Arsenal had seen nearly 75% of the ball in the first 20 minutes and Welbeck had Arsenal's best chance since Lacazette's opener.
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In the build up to the Ramsey's equaliser Mesut Ozil got away with a pretty blatant handball that had VAR been in use definitely would have been spotted. But for Arsenal the same old problems at the back resurfaced in worrying fashion in their curtain raiser with Leicester. Too early to start pointing fingers at our defence as we had only one natural CB play in defence but our attack was terrifying without our explosive star man Alexis Sanchez.
After being knocked down, Leicester got right back up with a second Vardy goal to take the 3-2 lead.
He drove at Arsenal's defence and his sublime whipped cross found the England worldwide who couldn't miss from inside the six-yard box completely against the run of play.
Giroud then sent the previously despondent Arsenal fans wild when he headed the victor from a corner, Leicester keeper Kasper Schmeichel only managing to turn the ball onto the underside of the bar before it bounced over the line.
Arsenal pulled level just before halftime through Danny Welbeck, who is, contrary to rumors, still alive.
Lacazette slipped as he went to turn and shoot and scuffed his shot to Kolasinac, who found himself one on one with Schmeichel.