Midfield: Victor Wanyama has recovered from a knee injury but the midfielder is lacking match practice so Harry Winks may start in the middle of the park alongside Mousa Dembele. Our live coverage lets you follow all the key moments as they happen.
Spurs are yet to buy any new players in this transfer window and Rose, 27, told The Sun they needed to sign "world-class players" and "not players you have to Google and say, 'Who's that?'" Find out by following our live matchcast.
Defensively, captain Jamaal Lascelles has shown a lot of potential.
While most players are typically linked with United, whether they are actually looking to move clubs or not, a move for Rose would not be within United's best interests.
The simplest solution is to move Eric Dier out to right-back with Belgian international's Tony Alderwiereld and Jan Vertonghen certain to start in the middle of defence. Dele Alli was poor right up until the moment Shelvey made a decision to use his ankle for leverage, Harry Kane was deep in his usual August slumber and Moussa Sissoko was Moussa Sissoko.
"I don't think it's a matter to joke about because with some of the worldwide players today, maybe one or two years ago, none of us knew them very well".
An injured Rose will not feature in Spurs' Premier League opener against Newcastle on Sunday, but, if Sadlier is to be believed, his ten-year affiliation with the North London club is unlikely to become eleven.
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Pochettino on his way to success?
Josh Onomah, another of the Spurs production line who was on the fringes of the first-team last season has joined Aston Villa on loan.
Eyebrows were raised when he replaced Nigel Adkins at Southampton in 2013, but he flourished in what was his first job in English football, and only his second managerial role overall.
Tottenham's 2016-17 campaign was also awash in nostalgia as the club bid farewell to White Hart Lane.
Spurs are already behind heading into the new season having signed no players at all.